WASP2.1 - Warning flags, design Advice & Screening Priorities WASP is the second step in the HARMLESS SSbD-DSS workflow
WASP 2.1 is an online tool to help industry with Safe and Sustainable by Design (SSbD) in the ideation and business case phase. With only 12 (+3 optional) questions, the user a) gains insight in which areas require specific attention, b) gets advice on how to best change the design and c) gets advice on what assays and guidelines to follow and which descriptors to measure (in the lab phase).
WASP is meant to be used In the early phases of innovation (the ideation and business case phase), after AMEA has been used to obtain the first categorization and design principles, but before entering the lab phase and the use of ASDI to help in selecting designs. In this phase, WASP helps industry with a simple questionnaire to a) provide warning flags (points of attention), b) provide design advice and c) assessment advice (including which descriptors to use in ASDI). WASP can also be used by regulators as part of the HARMLESS Early Warning System (EWS).
What is WASP?
WASP is an online tool that provides Safe and Sustainable by Design (SSbD) advice in early phases of innovation. After answering 12 main questions (and 3 optional ones), WASP provides the user with:
- Warning flags - It attends the user on particular points of attention that may require further investigation to be able to waive a concern or follow-up with further assessment to monitor it
- Design Advice - It provides design principles that may help to create better SSbD design versions
- Screening Prioritization - It provides assessment advice to further assess the concerns and to help prioritize the alternative SSbD versions regarding SSbD. This includes advice on what assays and guidelines to follow and which descriptors to measure (in the lab phase of the project)
WASP was created by the combined effort of several partners of the HARMLESS project, i.e. TNO, BASF, BfR, CIT and TEMASOL. Inspired by tools such as LICARA Innovation Scan, StoffenManager Nano, Early4AdMa and the Swiss precautionary matrix, but realizing that many existing tools are hampered because they A) may be laborious to fill in, B) ask for information that is not yet available in the early phases of development and C) may cover only a particular subset of aspects. Therefore, only the most useful and relevant questions for SSbD were redesigned into WASP and further extended to create a quick screening tool that provides points of attention as well as design and assessment advice.
Within the SSbD-DSS the user is guided through a SSbD workflow that follows the innovation stages from early to pilot phase. The first step in this SSbD workflow is AMEA, the second step is WASP and the third step is ASDI. In fact, WASP will provide a list of descriptors to be measured/assessed in ASDI
Literature
Publications about WASP are forthcoming.
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More about SSbD at TNO:
- The future of chemicals is Safe and Sustainable by Design (Oct 2024)
- SSbD presents significant opportunities for the Dutch chemical sector (Aug 2024)
- BASF and TNO collaborate on Decision Support for SSbD (July 2024)
- Safe and sustainable chemicals drives opportunities and transitions (July 2024)
- Safe chemical innovations | TNO
- TNO’s approach for safe and sustainable chemicals innovation (May 2024)
- The future of chemicals is safe and sustainable by design (Publication 2024)
- Application of tiered human health and environmental risk assessment to develop safe and sustainable by design perovskite-based devices (Publication 2024)
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 953183.