DIAMONDS
A GENERIC DATA MANAGEMENT AND INTEGRATION PLATFORM FOR THE LIFE SCIENCESDIAMONDS brings together Data, Knowledge and Algorithms. Data ranges from Clinical studies and Omics data to Personalized Health data. Traceable from original Raw measurements to Cleaned, Processed data ready to use. Knowledge ranges from Biological Knowledge from Curated databases and Textmining to manually Curated Triples from our Experts. All captured and connected to Source information through Standardized Pipelines and Workflows Protocols. Diverse tools and algorithms such as Statistical tools, Text mining methods, Scripts, Decision Trees, Bayesian/Dynamic Networks and Network Visualization.
DIAMONDS highlights
Summary of highlighted projects and modules in DIAMONDS
Interval Censored Bayesian Stacked Survival Model
The Interval Censored Bayesian Stacked Survival Model uses the log-likelihood estimation of different interval censored survival models based on different distributions to create a combined model that represents the data more accurately. Model stacking combines selected models by giving each model a weight. This approach can be used for generating population ED curves.
Read more about "interval censored bayesian stacked survival model"HARMLESS SSbD-DSS
Within the HARMLESS project, TNO has developed a Decision Support System to help industry make products with nano-materials that are Safe-&-Sustainable-by-Design (including complex nano-materials and high-aspect ratio nano-materials).
Read more about "harmless ssbd-dss"Nano Exposure Quantifier
The Nano Exposure Quantifier (NEQ) is a quantitative exposure assessment tool. It is designed to assist users in the safe-by-design process and decisions to reduce risk as a result from working with manufactured nanomaterials. The NEQ offers a Tiered approach by adapting the questions based on the depth of information the user can provide allowing anywhere between a Tier-1 and a Tier-2 approach.
Read more about "nano exposure quantifier"WASP2.1 - Warning flags, design Advice & Screening Priorities
WASP 2.1 is an online tool to help industry with Safe and Sustainable by Design (SSbD) in the ideation and business case phase. With only 12 (+3 optional) questions, the user a) gains insight in which areas require specific attention, b) gets advice on how to best change the design and c) gets advice on what assays and guidelines to follow and which descriptors to measure (in the lab phase).
Read more about "wasp2.1 - warning flags, design advice & screening priorities"